Tuesday, January 10, 2012

Entire Animal Genome Sequenced For $1,000

Entire Animal Genome Sequenced For $1,000

Life Technologies has launched the new Benchtop Ion Proton Sequencer, which can actuate the absolute animal genome for $1,000, in as little as one day. Previously, it had taken the apparatus anywhere from weeks, and alike months to arrangement a animal genome, and would bulk amid $5,000 and $10,000.
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Many ample medical practices, including Yale School of Medicine, Baylor College of Medicine, and The Broad Institute, already accept their own IonProton Sequencers.

Richard Gibbs, Administrator of the Animal Genome Sequencing Center at Baylor College of Medicine stated:

    "A genome arrangement for $1,000 was a pipe-dream, aloof a few years ago. A $1,000 genome in beneath than one day was not alike on the radar, but will transform the analytic applications of sequencing."




Ion Proton Sequencer

Dr. Richard Lifton, Chair of the Department of Genetics, Yale School of Medicine, said:

    "Cost, acceleration and accurateness are key elements in the use of DNA sequencing for both disease-gene assay and analytic utility. The abstruse advances in the new Ion Proton™ apparatus affiance to be game-changing for both assay and analytic applications."



Dr. Chad Nusbaum, co-director of the Broad Institute's Genome Sequencing and Assay Program agrees:

    "We are aflame about the paradigm-shifting abeyant of the new Proton Sequencer, which projects to arrangement a animal genome in aloof a few hours with alone one run on a distinct machine. The platform's acceleration and ability affiance to accredit both all-embracing assay and new analytic applications."



The aggregation says it is appointment the Ion PGM for approval from the FDA (Food and Drug Administration) this year. The apparatus is able to arrangement genes, baby genomes, panels of genes, and is additionally ideal for gene announcement profiling. All of these advances will be fabricated accessible for as little as $99 per chip. Its acceleration and artlessness accomplish it an ideal applicant to eventually be acclimated in diagnostics.


ionproton
Ion Proton Sequencer Chip


The Ion Proton Sequencer will additionally be able to arrangement exomes, which are regions in the DNA that cipher for protein, and animal genomes. The dent will be accessible to the accessible ancient in the abutting 6 months. The Ion Proton ll Dent will be accessible 6 months later, and will focus on sequencing accomplished animal genomes. Additionally, a third chip, the OneTouch system, will be advantageous for automating arrangement prep; an added Ion Proton Torrent Server will accomplish primary and accessory analysis.

Dr. Jonathan M. Rothberg, Founder and CEO of the Ion Torrent division, said:

    "Just six months afterwards our aboriginal semiconductor sequencing dent was released, bodies acclimated it to break the German E. coli outbreak, sequencing the baneful ache in aloof a brace of hours. Now, six months afterwards we're developing a dent that's 1,000 times added able than that to arrangement an absolute animal genome in about the aforementioned bulk of time. That's the ability that semiconductors accompany to sequencing."



The device's software is advised to asses and appraise an absolute genome aural 24 hours, on a stand-alone server. This does abroad with the informatics cartage jam and acutely aerial IT and basic investment, which historically has consistently been a albatross with optical based sequencers.

Interpreting the abiogenetic advice for analytic and analysis decisions has consistently been a claiming in accomplished genome sequencing. To accomplish this simpler, the Ion Torrent is teaming up with Carnegie Mellon University to appear up with a software to abetment bloom affliction professionals in compassionate the abiogenetic advice for use.

Yale Medical School is additionally bond with Ion Torrent to actualize with the best applicative way for analytic development and advertent genes, as a way to added appraise genome sequencing in a medical practice.

Robert F. Murphy, administrator of the Lane Center for Computational Biology concludes:

    "The huge aberration in animal genome arrangement amid individuals has consistently been an obstacle to compassionate how to use arrangement advice to advance animal health. We accept new apparatus acquirements approaches will accredit estimation of claimed genome sequences to advice doctors analyze and adviser analysis in the abreast future."



Life Technologies Corp's allotment amount rose 9.1% by mid-morning today, afterwards aggressive impressively yesterday.

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